PIPA558389

SPAG6 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA558389-Each-of-1 In Stock ₹ 51,486.50

PIPA558389 - Each of 1

₹ 51,486.50

In Stock

Quantity

1

Base Price: ₹ 51,486.50

GST (18%): ₹ 9,267.57

Total Price: ₹ 60,754.07

Antigen

SPAG6

Classification

Polyclonal

Conjugate

Unconjugated

Gene

SPAG6

Gene Alias

axoneme central apparatus protein; CT141; PF16; protein PF16 homolog; Repro-SA-1; RGD1310892; SPAG6; Spag6l; sperm associated antigen 6; sperm associated antigen 6 like; sperm flagellar protein; Sperm-associated antigen 6; testicular tissue protein Li 176

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

9576

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunohistochemistry, Western Blot

Concentration

0.4 mg/mL

Formulation

PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.

O75602

Gene Symbols

SPAG6

Immunogen

Recombinant protein corresponding to Human SPAG6

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • Immunogen sequence: AVPLLVLCIQ EPEIALKRIA ASALSDIAKH SPELAQTVVD AGAVAHLAQM ILNPDAKLKH QILSALSQVS KHSVDLAEMV VEA Highest antigen sequence identity to the following orthologs: Mouse - 92%, Rat - 92%
  • The correlation of anti-sperm antibodies with cases of unexplained infertility implicates a role for these antibodies in blocking fertilization
  • Improved diagnosis and treatment of immunologic infertility, as well as identification of proteins for targeted contraception, are dependent on the identification and characterization of relevant sperm antigens
  • The protein expressed by this gene is recognized by anti-sperm antibodies from an infertile man
  • This protein localizes to the tail of permeabilized human sperm and contains eight contiguous armadillo repeats, a motif known to mediate protein-protein interactions
  • Studies in mice suggest that this protein is involved in sperm flagellar motility and maintenance of the structural integrity of mature sperm
  • Alternatively spliced variants that encode different protein isoforms have been described but the full-length sequences of only two have been determined.