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PIPA558614

NUDT15 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA558614-Each-of-1 In Stock ₹ 48,905.50

PIPA558614 - Each of 1

₹ 48,905.50

In Stock

Quantity

1

Base Price: ₹ 48,905.50

GST (18%): ₹ 8,802.99

Total Price: ₹ 57,708.49

Antigen

NUDT15

Classification

Polyclonal

Conjugate

Unconjugated

Gene

NUDT15

Gene Alias

6530403O17; 7,8-dihydro-8-oxoguanine-triphosphatase NUDT15; 8-oxo-dGTPase NUDT15; A730068G11Rik; mMTH2; MTH2; MutT homolog 2; nucleoside diphosphate-linked moiety X motif 15; Nucleoside diphosphate-linked to another moiety X hydrolase 15; Nucleotide triphosphate diphosphatase NUDT15; nudix (nucleoside diphosphate linked moiety X)-type motif 15; nudix hydrolase 15; Nudix motif 15; nudix-type motif 15; NUDT15; NUDT15D; probable 7,8-dihydro-8-oxoguanine triphosphatase NUDT15; probable 8-oxo-dGTP diphosphatase NUDT15; RP11-90M2.1

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

55270

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunohistochemistry

Concentration

0.3 mg/mL

Formulation

PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.

Q9NV35

Gene Symbols

NUDT15

Immunogen

Recombinant protein corresponding to Human NUDT15

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

Description

  • Immunogen sequence: EKENYHYVTI LMKGEVDVTH DSEPKNVEPE KNESWEWVPW EELPPLDQLF WGLRCLKEQG YDPFKEDLNH LVGYKGNHL Highest antigen sequence identity to the following orthologs: Mouse - 90%, Rat - 90%
  • Mediates the hydrolysis of some nucleoside diphosphate derivatives
  • Can degrade 8-oxo-dGTP in vitro, suggesting that it may remove an oxidatively damaged form of guanine (7,8-dihydro-8-oxoguanine) from DNA and the nucleotide pool, thereby preventing misincorporation of 8-oxo-dGTP into DNA thus preventing A:T to C:G transversions
  • Its substrate specificity in vivo however remains unclear
  • May have a role in DNA synthesis and cell cycle progression throught the interaction with PCNA.