PIPA558710

BANF1 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA558710-Each-of-1 In Stock ₹ 52,065.00

PIPA558710 - Each of 1

₹ 52,065.00

In Stock

Quantity

1

Base Price: ₹ 52,065.00

GST (18%): ₹ 9,371.70

Total Price: ₹ 61,436.70

Antigen

BANF1

Classification

Polyclonal

Conjugate

Unconjugated

Gene

BANF1

Gene Alias

Baf; Banf1; barrier to autointegration factor 1; barrier-to-autointegration factor; Barrier-to-autointegration factor, N-terminally processed; BCRG1; Bcrp1; breakpoint cluster region protein 1; Breakpoint cluster region protein, uterine leiomyoma, 1; Breakpoint cluster region protein, uterine leiomyoma, 1; barrier to autointegration factor; D14S1460; L2bp1; L2bp1/Baf; Lap2 binding protein 1; LAP2-binding protein 1; NGPS

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

8815

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry

Concentration

0.05 mg/mL

Formulation

PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.

O75531

Gene Symbols

BANF1

Immunogen

Recombinant protein corresponding to Human BANF1

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • Immunogen sequence: MTTSQKHRDF VAEPMGEKPV GSLAGIGEVL GKKLEERGFD KAYVVLGQFL VLKKDEDLFR EWLKDTCGAN AKQSRDCFGC Highest antigen sequence identity to the following orthologs: Mouse - 96%, Rat - 96%
  • Barrier-to-autointegration factor 1 (BANF1) is a conserved chromatin protein that non-specifically binds double-stranded DNA
  • BANF1 also interacts with a family of nuclear proteins that include LAP2, emerin, and MAN1
  • It is also a host cell component of retroviral pre-integration complexes (PICs), including that of HIV
  • BANF1 will bind to p55 Gag (the structural precursor of HIV-1 virions) as well as its cleaved product matrix
  • In addition to being a host cell component of the PIC, it is thought that BANF1 is also present at low levels in incoming virions, and thus might contribute to the assembly or activity of HIV-1 PICs through direct binding to matrix as well as DNA.