ABH1 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA560609-Each-of-1 | In Stock | ₹ 48,905.50 |
PIPA560609 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 48,905.50
GST (18%): ₹ 8,802.99
Total Price: ₹ 57,708.49
Antigen
ABH1
Classification
Polyclonal
Conjugate
Unconjugated
Gene
ALKBH1
Gene Alias
2700073G19Rik; Abh; ABH1; alkB; alkB homolog 1, histone H2A dioxygenase; alkB, alkylation repair homolog 1; alkB, alkylation repair homolog 1 (E. coli); ALKBH; Alkbh1; Alkylated DNA repair protein alkB homolog 1; alkylation repair, alkB homolog; alpha-ketoglutarate-dependent dioxygenase ABH1; DNA 6mA demethylase; DNA demethylase ALKBH1; DNA lyase ABH1; DNA N6-methyl adenine demethylase; DNA N6-methyl adenine demethylase ALKBH1; DNA oxidative demethylase ALKBH1; hABH; mRNA N(3)-methylcytidine demethylase; Nucleic acid dioxygenase ALKBH1; tRNA N1-methyl adenine demethylase
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
8846
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Immunohistochemistry, Western Blot
Concentration
0.3 mg/mL
Formulation
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.
Q13686
Gene Symbols
ALKBH1
Immunogen
Recombinant protein corresponding to Human ABH1
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Immunogen sequence: SMVEPCSLED WQVCASYLKT ARVNMTVRQV LATDQNFPLE PIEDEKRDIS TEGFCHLDDQ NSEVKRARIN Highest antigen sequence identity to the following orthologs: Mouse - 74%, Rat - 74%
- This gene encodes a homolog to the E
- coli alkB gene product
- The E
- coli alkB protein is part of the adaptive response mechanism of DNA alkylation damage repair
- It is involved in damage reversal by oxidative demethylation of 1-methyladenine and 3-methylcytosine
- Dioxygenase that repairs alkylated single-stranded DNA and RNA containing 3-methylcytosine by oxidative demethylation
- Requires molecular oxygen, alpha-ketoglutarate and iron
- May have a role in placental trophoblast lineage differentiation
- Has DNA lyase activity and introduces double-stranded breaks at abasic sites
- Cleaves both single-stranded DNA and double-stranded DNA at abasic sites, with the greatest activity towards double-stranded DNA with two abasic sites.