Cystatin M Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA560874-Each-of-1 | In Stock | ₹ 52,332.00 |
PIPA560874 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 52,332.00
GST (18%): ₹ 9,419.76
Total Price: ₹ 61,751.76
Antigen
Cystatin M
Classification
Polyclonal
Conjugate
Unconjugated
Gene
CST6
Gene Alias
1110017E11Rik; AA960480; CST6; Cstb; cystatin 6; cystatin B; cystatin E/M; cystatin M; cystatin M/E; cystatin N; cystatin-6; Cystatin-B; cystatin-E; Cystatin-M; cysteine proteinase inhibitor; harlequin ichthyosis; harlequin ichthysosis; ichq; N28197; Stefin-B; Stfb
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
1474
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Immunohistochemistry
Concentration
0.05 mg/mL
Formulation
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.
Q15828
Gene Symbols
CST6
Immunogen
Recombinant protein corresponding to Human Cystatin M
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Immunogen sequence: SNSIYYFRDT HIIKAQSQLV AGIKYFLTME MGSTDCRKTR VTGDHVDLTT CPLAAGAQQE KLRCDFEVLV VPWQNSSQLL KH Highest antigen sequence identity to the following orthologs: Mouse - 72%, Rat - 74%
- The cystatin superfamily is a well-established family of cysteine protease inhibitors
- Cystatins A and B (type 1) are mainly intracellular; cystatins C, D, E/M, F, G, S, SN and SA cystatins are extracellular (type 2); and the kininogens are type 3 cystatins which are intravascular proteins
- All true cystatins inhibit cysteine peptidases of the papain family, such as cathepsins, and some also inhibit legumain family enzymes
- Cystatin SA, cystatin S and cystatin SN are found primarily in saliva
- Cystatin S and SN can also be expressed in tears, urine and seminal fluid
- Cystatin C is a related protein which is expressed in brain, thymus, ovary, epididymis and vas deferens
- Cystatin D protects against proteinases in the oral cavity, while Cystatin E/M and F moderate the inhibition of cathepsin proteins
- The fetuins, part of the cystatin superfamily, are secretable proteins that influence osteogenesis and bone resorption, regulation of the insulin and hepatocyte growth factor receptors and the response to systemic inflammation
- High molecular weight kininogen (Kininogen HC) and low molecular weight kininogen (Kininogen LC) have varied roles, though they both inhibit the thrombin- and plasmin-induced aggregation of thrombocytes.