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PIPA561187

EFCAB4A Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA561187-Each-of-1 In Stock ₹ 48,905.50

PIPA561187 - Each of 1

₹ 48,905.50

In Stock

Quantity

1

Base Price: ₹ 48,905.50

GST (18%): ₹ 8,802.99

Total Price: ₹ 57,708.49

Antigen

EFCAB4A

Classification

Polyclonal

Conjugate

Unconjugated

Gene

CRACR2B

Gene Alias

6330520A15Rik; BC026645; Ca2+ release-activated Ca2+ (CRAC) channel regulator 2B; calcium release activated channel regulator 2B; calcium release-activated calcium channel regulator 2B; Calcium release-activated channel regulator 2B; CRAC channel regulator 2B; CRAC regulator 2B; Cracr2a; CRACR2B; Efcab4; EFCAB4A; EF-hand calcium binding domain 4A; EF-hand calcium-binding domain-containing protein 4A; RGD1560911

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

283229

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunohistochemistry, Western Blot

Concentration

0.4 mg/mL

Formulation

PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.

Q8N4Y2

Gene Symbols

CRACR2B

Immunogen

Recombinant protein corresponding to Human EFCAB4A

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

Description

  • Immunogen sequence: LEAVFESLDQ AHTGFLTARE FCLGLGMFVG VASAQGANPC RTPEETFESG GLDVQGTAGS LDEE Highest antigen sequence identity to the following orthologs: Mouse - 77%, Rat - 77%
  • EFCAB4A, also known as Calcium release-activated calcium channel regulator 2B, is a novel Ca2+-binding EF-hand protein that is thought to play a key role in store-operated Ca2+ entry in T-cells by regulating CRAC channel activation, but the detailed function is still under investigation
  • It is likely to play a similar role as the related protein EFCAB4B, which acts as a cytoplasmic calcium-sensor that forms a complex with ORAI1 and STIM1 at the junctional regions between the plasma membrane and the endoplasmic reticulum upon low Ca2+ concentration.