NALP11 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA561235-Each-of-1 | In Stock | ₹ 48,905.50 |
PIPA561235 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 48,905.50
GST (18%): ₹ 8,802.99
Total Price: ₹ 57,708.49
Antigen
NALP11
Classification
Polyclonal
Conjugate
Unconjugated
Gene
NLRP11
Gene Alias
CLR19.6; NACHT, leucine rich repeat and PYD containing 11; NACHT, LRR and PYD domains-containing protein 11; NALP11; NLR family pyrin domain containing 11; NLR family, pyrin domain containing 11; NLRP11; NOD17; Nucleotide-binding oligomerization domain protein 17; nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domain containing 11; PAAD- and NACHT-containing protein 10B; PAAD-and NACHT domain-containing protein 10; PAN10; PYPAF6; PYPAF7; PYRIN-containing APAF1-like protein 6
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
204801
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Immunohistochemistry, Western Blot
Concentration
0.2 mg/mL
Formulation
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.
P59045
Gene Symbols
NLRP11
Immunogen
Recombinant protein corresponding to Human NALP11
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Immunogen sequence: HLGNDGVAKL LESLISPDCV LKVVGLPLTG LNTQTQQLLM TVKERKPSLI FLSETWSLKE GREIGVTPAS QPGSIIPNSN LDYMFFKFPR MSAAMRTSNT ASR Highest antigen sequence identity to the following orthologs: Mouse - 23%, Rat - 23%
- NALP11 is a 1033 amino acid containing cytoplasmic protein belonging to the NLRP family with a DAPIN domain, six LRR (leucine-rich) repeats and a NACHT domain
- Reports suggest that it is a short NALP involved in inflammation potential
- NALP proteins are implicated in the activation of proinflammatory caspases (e.g., CASP1) via their involvement in multiprotein complexes called inflammasomes
- The DAPIN domain is necessary and sufficient for suppression of NF-kappa B activation induced by TNF and for inducing IL-1B secretion in collaboration with Caspase-1
- It is involved in interaction with PYCARD.