POLR3H Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA561325-Each-of-1 | In Stock | ₹ 48,905.50 |
PIPA561325 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 48,905.50
GST (18%): ₹ 8,802.99
Total Price: ₹ 57,708.49
Antigen
POLR3H
Classification
Polyclonal
Conjugate
Unconjugated
Gene
POLR3H
Gene Alias
5031409G22Rik; DNA-directed RNA polymerase III subunit 22.9 kDa polypeptide; DNA-directed RNA polymerase III subunit H; DNA-directed RNA polymerase III subunit RPC8; KIAA1665; POLR3H; polymerase (RNA) III (DNA directed) polypeptide H; polymerase (RNA) III (DNA directed) polypeptide H (22.9kD); polymerase (RNA) III subunit H; RNA nucleotidyltransferase (DNA-directed); RNA polymerase III subunit 22.9 kDa subunit; RNA polymerase III subunit C7; RNA polymerase III subunit C8; RNA polymerase III subunit H; RPC22.9; RPC8
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
171568
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Immunocytochemistry, Immunohistochemistry, Western Blot
Concentration
0.3 mg/mL
Formulation
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.
Q9Y535
Gene Symbols
POLR3H
Immunogen
Recombinant protein corresponding to Human POLR3H
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Immunogen sequence: GFFDDILIPP ESLQQPAKFD EAEQVWVWEY ETEEGAHDLY MDTGEEIRFR VVDESFVDTS PTGPSSADAT TSSEELPKKE APYTLVG Highest antigen sequence identity to the following orthologs: Mouse - 97%, Rat - 97%
- RPC8 is DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
- Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs
- It is plays a key role in sensing and limiting infection by intracellular bacteria and DNA viruses
- It is acting as nuclear and cytosolic DNA sensor involved in innate immune response
- It can sense non-self dsDNA that serves as template for transcription into dsRNA
- The non-self RNA polymerase III transcripts, such as Epstein-Barr virus-encoded RNAs (EBERs) induce type I interferon and NF-Kappa-B through the RIG-I pathway.