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PIPA561425

eIF3c Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA561425-Each-of-1 In Stock ₹ 48,905.50

PIPA561425 - Each of 1

₹ 48,905.50

In Stock

Quantity

1

Base Price: ₹ 48,905.50

GST (18%): ₹ 8,802.99

Total Price: ₹ 57,708.49

Antigen

eIF3c

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Eif3c

Gene Alias

110kDa; 3230401O13Rik; cell migration-inducing protein 17; eIF3 p110; eIF3 p110 {ECO:0000255; eIF3c; eIF3c {ECO:0000255; EIF3CL; eIF3-p110; EIF3S8; eukaryotic translation initiation factor 3 subunit 8; eukaryotic translation initiation factor 3 subunit 8 {ECO:0000255; Eukaryotic translation initiation factor 3 subunit C; eukaryotic translation initiation factor 3 subunit C {ECO:0000255; eukaryotic translation initiation factor 3, subunit 8 (110 kDa); eukaryotic translation initiation factor 3, subunit 8 (110kD); eukaryotic translation initiation factor 3, subunit 8, 110kDa; eukaryotic translation initiation factor 3, subunit C; extra-toes spotting; HAMAP-Rule:MF_03002}; NIPIL(A3); NipilA3; NIPI-like protein; Xs; Xsl

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

8663

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry

Concentration

0.10 mg/mL

Formulation

PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.

Q99613

Gene Symbols

Eif3c

Immunogen

Recombinant protein corresponding to Human eIF3c

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

Description

  • Immunogen sequence: YYKFDYKAHQ RQLTPPEGSS KSEQDQAENE GEDSAVLMER LCKYIYAKDR TDRIRTCAIL CHIYHHALHS Highest antigen sequence identity to the following orthologs: Mouse - 100%, Rat - 100%
  • Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis
  • The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC)
  • The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition
  • The eIF-3 complex is also required for disassembly and recycling of post termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation.