RAPGEF5 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA563494-Each-of-1 | In Stock | ₹ 48,905.50 |
PIPA563494 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 48,905.50
GST (18%): ₹ 8,802.99
Total Price: ₹ 57,708.49
Antigen
RAPGEF5
Classification
Polyclonal
Conjugate
Unconjugated
Gene
RAPGEF5
Gene Alias
4932413M22; C86120; D030051B22Rik; GFR; guanine nucleotide exchange factor; guanine nucleotide exchange factor for Rap1; KIAA0277; mKIAA0277; mmr-gef; Mras regulated guanine nucleotide exchange factor; M-Ras-regulated GEF; M-Ras-regulated Rap GEF; MRGEF; MR-GEF; Rap guanine nucleotide exchange factor (GEF) 5; Rap guanine nucleotide exchange factor 5; RAPGEF5; Related to Epac; REPAC; RGD1562891; rMR-GEF; tcag7.1034
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
9771
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Immunohistochemistry
Concentration
0.05 mg/mL
Formulation
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.
Q92565
Gene Symbols
RAPGEF5
Immunogen
Recombinant protein corresponding to Human RAPGEF5
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Immunogen sequence: EEDLALVAIT FSGEKHELQP NDLVISKSLE ASGRIYVYRK DLADTLNPFA ENEESQQRSM RILGMNTWDL Highest antigen sequence identity to the following orthologs: Mouse - 96%, Rat - 96%
- Members of the RAS subfamily of GTPases function in signal transduction as GTP/GDP-regulated switches that cycle between inactive GDP- and active GTP-bound states
- Guanine nucleotide exchange factors (GEFs), such as Repac, serve as RAS activators by promoting acquisition of GTP to maintain the active GTP-bound state and are the key link between cell surface receptors and RAS activation
- Repac, also known as Rap guanine nucleotide exchange factor 5 (RAPGEF5), is a 580 amino acid protein that is expressed in brain and testis, with weaker expression in heart, placenta, lung, pancreas and small intestine
- Existing as two alternatively spliced isoforms, the Repac gene is conserved in cow, mouse and rat
- The gene that encodes Repac maps to human chromosome 7p15.3, with high expression of this region linking to positive response to erlotinib therapy for those with non-small-cell lung cancer.