alpha-2b Adrenergic Receptor Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA564258-Each-of-1 | In Stock | ₹ 48,905.50 |
PIPA564258 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 48,905.50
GST (18%): ₹ 8,802.99
Total Price: ₹ 57,708.49
Antigen
alpha-2b Adrenergic Receptor
Classification
Polyclonal
Conjugate
Unconjugated
Gene
ADRA2B
Gene Alias
[a]2B; ADA2B; Adra2b; Adra-2b; ADRA2B adrenergic, alpha-2B-, receptor; ADRA2L1; ADRA2RL1; ADRARL1; Adrenergic alpha2B- receptor class III; adrenergic receptor, alpha 2b; adrenergic, alpha-2B-, receptor; Adrenergic, alpha2B-, receptor class III; adrenoceptor alpha 2B; alpha-2 adrenergic receptor subtype C2; alpha-2-adrenergic receptor-like 1; alpha2B; alpha-2B adrenergic receptor; Alpha-2B adrenoceptor; alpha-2B adrenoreceptor; ALPHA2BAR; alpha-2BAR; alpha2-C2; FAME2; G-protein coupled receptor; subtype alpha2-C2
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
151
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Immunohistochemistry
Concentration
0.2 mg/mL
Formulation
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.
P18089
Gene Symbols
ADRA2B
Immunogen
Recombinant protein corresponding to Human alpha-2b Adrenergic Receptor
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Immunogen sequence: IAKRSNRRGP RAKGGPGQGE SKQPRPDHGG ALASAKLPAL ASVASAREVN Highest antigen sequence identity to the following orthologs: Mouse - 57%, Rat - 55%
- Alpha-2-adrenergic receptors are members of the G protein-coupled receptor superfamily
- They include 3 highly homologous subtypes: alpha2A, alpha2B, and alpha2C
- These receptors have a critical role in regulating neurotransmitter release from sympathetic nerves and from adrenergic neurons in the central nervous system
- Alpha 2B adrenergic receptor subtype was observed to associate with eIF-2B, a guanine nucleotide exchange protein that functions in regulation of translation
- A polymorphic variant of the alpha2B subtype, which lacks 3 glutamic acids from a glutamic acid repeat element, was identified to have decreased G protein-coupled receptor kinase-mediated phosphorylation and desensitization; this polymorphic form is also associated with reduced basal metabolic rate in obese subjects and may therefore contribute to the pathogenesis of obesity
- Alpha 2B adrenergic receptor gene contains no introns in either its coding or untranslated sequences.