PIPA564322
AMOT Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA564322-Each-of-1 | In Stock | ₹ 52,599.00 |
PIPA564322 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 52,599.00
GST (18%): ₹ 9,467.82
Total Price: ₹ 62,066.82
Antigen
AMOT
Classification
Polyclonal
Conjugate
Unconjugated
Gene
AMOT
Gene Alias
AMOT; Angiomotin; angiomotin p130 isoform; angiomotin p80 isoform; CAG-2; D0Kist1; KIAA1071; RGD1564027; si:dkey-13f9.6; Sii6; wu:fj21a07
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
154796
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Immunohistochemistry
Concentration
0.2 mg/mL
Formulation
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.
Q4VCS5
Gene Symbols
AMOT
Immunogen
Recombinant protein corresponding to Human AMOT
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Immunogen sequence: LSERLMQMSL ATSGVKAHPP VTSAPLSPPQ PNDLYKNPTS SSEFYKAQGP LPNQHSLKGM EHRG Highest antigen sequence identity to the following orthologs: Mouse - 95%, Rat - 95%
- AMOT (Angiomotin) belongs to the motin family of angiostatin binding proteins characterized by conserved coiled-coil domains and C-terminal PDZ binding motifs
- AMOT plays a central role in tight junction maintenance via the complex formed with ARHGAP17 - which acts by regulating the uptake of polarity proteins at tight junctions
- AMOT is expressed predominantly in endothelial cells of capillaries as well as larger vessels of the placenta where it may mediate the inhibitory effect of angiostatin on tube formation and the migration of endothelial cells toward growth factors during the formation of new blood vessels.