TRIP10 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA565319-Each-of-1 | In Stock | ₹ 48,905.50 |
PIPA565319 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 48,905.50
GST (18%): ₹ 8,802.99
Total Price: ₹ 57,708.49
Antigen
TRIP10
Classification
Polyclonal
Conjugate
Unconjugated
Gene
Trip10
Gene Alias
AI646975; Cdc42 interacting protein-4; cdc42-interacting protein 4; Cip4; hSTP; protein Felic; Salt tolerant protein; salt tolerator; STOT; STP; thyroid hormone receptor interactor 10; thyroid receptor-interacting protein 10; TR-interacting protein 10; TRIP10; TRIP-10
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
9322
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Immunocytochemistry
Concentration
0.3 mg/mL
Formulation
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.
Q15642
Gene Symbols
Trip10
Immunogen
Recombinant Human TRIP10
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Immunogen sequence: LQRFNRDQAHF YFSQMPQIFD KLQDMDERRA TRLGAGYGLL SEAELEVVPI IA Highest antigen sequence identity to the following orthologs - mouse 96%, rat 89%
- Required for translocation of GLUT4 to the plasma membrane in response to insulin signaling
- Required to coordinate membrane tubulation with reorganization of the actin cytoskeleton during endocytosis
- Binds to lipids such as phosphatidylinositol 4,5-bisphosphate and phosphatidylserine and promotes membrane invagination and the formation of tubules
- Also promotes CDC42-induced actin polymerization by recruiting WASL/N-WASP which in turn activates the Arp2/3 complex
- Actin polymerization may promote the fission of membrane tubules to form endocytic vesicles
- Required for the formation of podosomes, actin-rich adhesion structures specific to monocyte-derived cells
- May be required for the lysosomal retention of FASLG/FASL.