PIPA565325

SPRY2 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA565325-Each-of-1 In Stock ₹ 48,905.50

PIPA565325 - Each of 1

₹ 48,905.50

In Stock

Quantity

1

Base Price: ₹ 48,905.50

GST (18%): ₹ 8,802.99

Total Price: ₹ 57,708.49

Antigen

SPRY2

Classification

Polyclonal

Conjugate

Unconjugated

Gene

SPRY2

Gene Alias

hSPRY2; IGAN3; MGC23039; protein sprouty homolog 2; sprouty 2; sprouty homolog 2; sprouty homolog 2 (Drosophila); sprouty RTK signaling antagonist 2; sprouty2; SPRY2; spry-2

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

10253

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunocytochemistry

Concentration

0.3 mg/mL

Formulation

PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.

O43597

Gene Symbols

SPRY2

Immunogen

Recombinant Human SPRY2

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • Immunogen sequence: PTVVPRPGLKP APRPSTQHKH ERLHGLPEHR QPPRLQHSQV HSSARAPLSR SISTVSSGSR SSTRTSTSSS SSEQ Highest antigen sequence identity to the following orthologs - mouse 97%, rat 93%
  • This gene encodes a protein belonging to the sprouty family
  • The encoded protein contains a carboxyl-terminal cysteine-rich domain essential for the inhibitory activity on receptor tyrosine kinase signaling proteins and is required for growth factor stimulated translocation of the protein to membrane ruffles
  • In primary dermal endothelial cells this gene is transiently upregulated in response to fibroblast growth factor two
  • This protein is indirectly involved in the non-cell autonomous inhibitory effect on fibroblast growth factor two signaling
  • The protein interacts with Cas-Br-M (murine) ectropic retroviral transforming sequence, and can function as a bimodal regulator of epidermal growth factor receptor/mitogen-activated protein kinase signaling
  • This protein may play a role in alveoli branching during lung development as shown by a similar mouse protein.