WAC Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA565336-Each-of-1 | In Stock | ₹ 48,905.50 |
PIPA565336 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 48,905.50
GST (18%): ₹ 8,802.99
Total Price: ₹ 57,708.49
Antigen
WAC
Classification
Polyclonal
Conjugate
Unconjugated
Gene
Wac
Gene Alias
1110067P07Rik; A230035H12Rik; AI256735; AI256776; BM-016; DESSH; Kiaa1844; PRO1741; RGD1562407; Wac; WW domain containing adaptor with coiled-coil; WW domain-containing adapter protein with coiled-coil; WW domain-containing adaptor with coiled-coil; WW domain-containing protein 4; Wwp4
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
51322
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Immunocytochemistry
Concentration
0.2 mg/mL
Formulation
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.
Q9BTA9
Gene Symbols
Wac
Immunogen
Recombinant Human WAC
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Immunogen sequence: NATVVPQNSSA RSTCSLTPAL AAHFSENLIK HVQGWPADHA EKQASRLREE AHNMGTIHMS EICTELKNLR SLVRVCEIQA TLR Highest antigen sequence identity to the following orthologs - mouse 89%, rat 88%
- The WW domain containing adaptor with coiled-coil protein (WAC) contains a WW domain that mediates protein-protein interactions and colocalizes with RNA splicing factor SC35
- Further studies have indicated that WAC is a functional partner of the RNF20/40 complex that ubiquitinates Histone H2B, and that WAC regulates H2B ubiquitination
- WAC targets RNF20/40 to associate with RNA polymerase II complex for H2B ubiquitination at active transcription sites
- WAC-dependent transcription is also important for cell-cycle checkpoint activation in response to genotoxic stress.