TOB1 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA565480-Each-of-1 | In Stock | ₹ 49,439.50 |
PIPA565480 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 49,439.50
GST (18%): ₹ 8,899.11
Total Price: ₹ 58,338.61
Antigen
TOB1
Classification
Polyclonal
Conjugate
Unconjugated
Gene
TOB1
Gene Alias
APRO5; APRO6; MGC104792; MGC34446; PIG49; proliferation-inducing gene 49; protein Tob1; Protein Tob1-like protein; TOB; TOB1; transducer of erbB2; Transducer of erbB-2 1; transducer of ERBB2, 1; transducer of ErbB-2.1; Trob; TROB1; Unknown (protein for MGC:134447)
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
10140
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Immunocytochemistry, Immunohistochemistry
Concentration
0.1 mg/mL
Formulation
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.
P50616
Gene Symbols
TOB1
Immunogen
Recombinant Human TOB1
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Immunogen sequence: STKMKNSGRSN KVARTSPINL GLNVNDLLKQ KAISSSMHSL YGLGLGSQQQ PQQQ Highest antigen sequence identity to the following orthologs - mouse 91%, rat 91%
- This gene encodes a member of the tob/btg1 family of anti-proliferative proteins that have the potential to regulate cell growth
- When exogenously expressed, this protein supresses cell growth in tissue culture
- The protein undergoes phophorylation by a serine/threonine kinase, 90 kDa ribosomal S6 kinase
- Interactions of this protein with the v-erb-b2 erythroblastic leukemia viral oncogene homolog 2 gene product p185 interferes with growth suppression
- This protein inhibits T cell proliferation and transcription of cytokines and cyclins
- The protein interacts with both mothers against decapentaplegic Drosophila homolog 2 and 4 to enhance their DNA binding activity
- This interaction inhibits interleukin 2 transcription in T cells.