PIPA565629

Septin-9 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA565629-Each-of-1 In Stock ₹ 48,905.50

PIPA565629 - Each of 1

₹ 48,905.50

In Stock

Quantity

1

Base Price: ₹ 48,905.50

GST (18%): ₹ 8,802.99

Total Price: ₹ 57,708.49

Antigen

Septin-9

Classification

Polyclonal

Conjugate

Unconjugated

Gene

SEPTIN9

Gene Alias

AF17q25; eighth septin; Eseptin; E-septin; KIAA0991; MLL septin-like fusion; MLL septin-like fusion protein; MLL septin-like fusion protein MSF-A; MSF; MSF1; NAPB; Ov/Br septin; ovarian/breast septin; PNUTL4; SEPT9; SeptD1; septin 9; septin D1; SEPTIN9; Septin-9; septin-like protein; Sint1; SL3-3 integration site 1 protein; SLP; Slpa

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

10801

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunocytochemistry

Concentration

0.4 mg/mL

Formulation

PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.

Q9UHD8

Gene Symbols

SEPTIN9

Immunogen

Recombinant Human Septin-9

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • Immunogen sequence: PAPVSQLQSRL EPKPQPPVAE ATPRSQEATE AAPSCVGDMA DTPRDAGLKQ APASRNEKAP VDFGYVGIDS Highest antigen sequence identity to the following orthologs - mouse 75%, rat 77%
  • The maf oncogene was identified by structural analysis of the AS42 avian transforming retrovirus genome
  • The Maf family is divided into two subclasses, large Mafs (vMaf, cMaf, MafB and Nrl) and small Mafs (MafF, MafK, and MafG)
  • Both subclasses contain leucinezipper motifs, which allow homodimerization as well as heterodimerization with a variety of other bZip transcription factors
  • Large Mafs also contain an acidic transactivation domain absent in the small Maf proteins
  • Although they do not possess inherent transactivation activity, small Maf proteins can act as positive regulators of transcription by targeting transcriptionally active dimerization partners to specific DNA regulatory elements
  • Conversely, small Mafs can act also as negative regulators of transcription by recruiting transcriptional repressors or by forming homodimers that can replace active dimers
  • Human MafF was isolated in a yeast one-hybrid system from a human myometrium cDNA library
  • Human MAFF encodes a 164 amino acids proten
  • Like other small MAFF proteins, it contains an extended leucine zipper structure and lacks an N-terminal transactivating domain
  • The three small Maf proteins have been implicated in a number of physiological processes, including development, differentiation, haematopoiesis and stress response
  • Interestingly, these three proteins regulate the stress response via different mechanisms.