PIPA565694
Cullin 9 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA565694-Each-of-1 | In Stock | ₹ 48,905.50 |
PIPA565694 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 48,905.50
GST (18%): ₹ 8,802.99
Total Price: ₹ 57,708.49
Antigen
Cullin 9
Classification
Polyclonal
Conjugate
Unconjugated
Gene
CUL9
Gene Alias
1810035I07Rik; CUL9; CUL-9; cullin 9; cullin-9; H7AP1; KIAA0708; mKIAA0708; p53-associated parkin-like cytoplasmic protein; PARC; parkin-like cytoplasmic p53 binding protein; RP3-330M21.2; UbcH7-associated protein 1
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
23113
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Immunocytochemistry
Concentration
0.1 mg/mL
Formulation
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.
Q8IWT3
Gene Symbols
CUL9
Immunogen
Recombinant Human Cullin 9
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Immunogen sequence: WKPNHKDYYNC SAMVSKAARQ EKRFQDYNER CTFHHQAREF AVNLRNRVSA IHEVPPPRSF TFLNDACQGL EQARKVLAYA CVYSFYSQDA EYMDVVEQQT ENLELHT Highest antigen sequence identity to the following orthologs - mouse 92%, rat 92%
- The continued localization of p53 to the nucleus is essential for its function as a tumor suppressor
- PARC, a large, Parkin-like ubiquitin ligase has recently been identified as a cytoplasmic anchor protein in p53-associated protein complexes
- In the absence of stress, PARC inactivation results in nuclear localization of p53 and activation of p53-dependent apoptosis, while overexpression of this protein promoted cytoplasmic sequestration of p53
- Surprisingly, PARC knockout mice were viable and exhibited no obvious phenotype, suggesting that other proteins, such as the highly related cullin family of E3 ubiquitin ligases, may perform similar functions in the absence of PARC
- Additionally, it has been suggested that p53 binding to PARC may serve to control PARC function.