PIPA565713

MIOS Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA565713-Each-of-1 In Stock ₹ 48,905.50

PIPA565713 - Each of 1

₹ 48,905.50

In Stock

Quantity

1

Base Price: ₹ 48,905.50

GST (18%): ₹ 8,802.99

Total Price: ₹ 57,708.49

Antigen

MIOS

Classification

Polyclonal

Conjugate

Unconjugated

Gene

MIOS

Gene Alias

C81488; FLJ20323; GATOR complex protein MIOS; H_DJ1159O04.1; meiosis regulator for oocyte development; MIO; Mios; Missing oocyte meiosis regulator homolog; missing oocyte, meiosis regulator, homolog; missing oocyte, meiosis regulator, homolog (Drosophila); RGD1308432; Sea4; WD repeat-containing protein mio; WUGSC:H_DJ1159O04.1

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

54468

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunocytochemistry

Concentration

0.1 mg/mL

Formulation

PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.

Q9NXC5

Gene Symbols

MIOS

Immunogen

Recombinant Human MIOS

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • Immunogen sequence: SISYSCSAVPH QGRGFSQYGV SGSPTKSKVT SCPGCRKPLP RCALCLINMG TPVSSCPGGT KSDEKVDLSK DKKLAQFNNW FTWCHNCRHG GHAGHMLSWF RDHAECPVSA CTCKCMQLD Highest antigen sequence identity to the following orthologs - mouse 98%, rat 98%
  • As a component of the GATOR subcomplex GATOR2, functions within the amino acid-sensing branch of the TORC1 signaling pathway
  • Indirectly activates mTORC1 and the TORC1 signaling pathway through the inhibition of the GATOR1 subcomplex (PubMed:23723238)
  • It is negatively regulated by the upstream amino acid sensors SESN2 and CASTOR1 (PubMed:25457612, PubMed:27487210)
  • [UniProt]