PIPA565761

MSRA Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA565761-Each-of-1 In Stock ₹ 48,905.50

PIPA565761 - Each of 1

₹ 48,905.50

In Stock

Quantity

1

Base Price: ₹ 48,905.50

GST (18%): ₹ 8,802.99

Total Price: ₹ 57,708.49

Antigen

MSRA

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Msra

Gene Alias

2310045J23Rik; 6530413P12Rik; cytosolic methionine-S-sulfoxide reductase; methionine sulfoxide reductase A; mitochondrial peptide methionine sulfoxide reductase; Msra; MSR-A; peptide met (O) reductase; peptide Met(O) reductase; peptide methionine sulfoxide reductase; peptide-methionine (S)-S-oxide reductase; PMSR; protein-methionine-S-oxide reductase

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

4482

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunocytochemistry

Concentration

0.1 mg/mL

Formulation

PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.

Q9UJ68

Gene Symbols

Msra

Immunogen

Recombinant Human MSRA

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • Immunogen sequence: AKQMEAALSSK ENYQKVLSEH GFGPITTDIR EGQTFYYAED YHQQYLSKNP NGYCGLGGTG VSCPVGIK Highest antigen sequence identity to the following orthologs - mouse 87%, rat 65%
  • Methionine sulfoxide reductase (MsrA) reduces methionine sulfoxide (MetO) residues in proteins and free MetO to Methionine (Met)
  • The catalytic activity of MsrA is dependent of bound metal and cofactors but it requires reducing equivalents from either DTT or a thioredoxin-regenerating system
  • MsrA plays an essential role in protecting cells against oxidative damage
  • The substrates of MsrA include calmodulin, HIV protease and a 1-proteinase-inhibitor
  • Recent studies indicate that there is a connection between MsrA and Alzheimer's disease in mammals.