GADD45A Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA565786-Each-of-1 | In Stock | ₹ 48,905.50 |
PIPA565786 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 48,905.50
GST (18%): ₹ 8,802.99
Total Price: ₹ 57,708.49
Antigen
GADD45A
Classification
Polyclonal
Conjugate
Unconjugated
Gene
GADD45A
Gene Alias
AA545191; DDIT 1; DDIT1; DDIT-1; DNA damage-inducible transcript 1 protein; DNA damage-inducible transcript-1; DNA-damage inducible transcript 1; DNA-damage-inducible transcript 1; GADD45; GADD45A; Gadd45alpha; growth arrest and DNA damage inducible alpha; growth arrest and DNA damage-inducible protein GADD45 alpha; growth arrest and DNA-damage-inducible 45 alpha; growth arrest and DNA-damage-inducible protein GADD45 alpha; growth arrest and DNA-damage-inducible, alpha
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
1647
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Immunocytochemistry
Concentration
0.05 mg/mL
Formulation
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.
P24522
Gene Symbols
GADD45A
Immunogen
Recombinant Human GADD45A
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Immunogen sequence: MTLEEFSAGEQ KTERMDKVGD ALEEVLSKAL SQ Highest antigen sequence identity to the following orthologs - mouse 91%, rat 88%
- GADD45 alpha, beta and gamma are an evolutionarily conserved, homologous family of nuclear proteins that function as stress sensors for cellular physiological and environmental damage
- GADD45 proteins are required for the activation of the G2/M checkpoint induced by UV radiation or alkylating agents
- GADD45-induced G2/M checkpoint is regulated through inactivation of Cdc2-cyclin B1 kinase
- GADD45 forms a complex with p21 and Cdc2, and may serve as core for interaction with other cell cycle regulators.