PIPA567748

TAS2R38 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA567748-Each-of-1 In Stock ₹ 46,146.50

PIPA567748 - Each of 1

₹ 46,146.50

In Stock

Quantity

1

Base Price: ₹ 46,146.50

GST (18%): ₹ 8,306.37

Total Price: ₹ 54,452.87

Antigen

TAS2R38

Classification

Polyclonal

Conjugate

Unconjugated

Gene

TAS2R38

Gene Alias

mt2r31; PTC; PTC bitter taste receptor; RGD:1560649}; T2R138; T2R26; T2r31; T2r38; T2r38 {ECO:0000312; T2R61; Tas2r138; Tas2r26; TAS2R38; taste 2 receptor member 38; taste receptor type 2 member 26; Taste receptor type 2 member 38; taste receptor type 2 member 61; taste receptor, type 2, member 138; taste receptor, type 2, member 38

Host Species

Rabbit

Purification Method

affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

387513, 500091, 5726

Content And Storage

-20°C

Form

Liquid

Applications

Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.

P59533, Q4VHE7, Q7TQA6

Gene Symbols

Tas2r138, TAS2R38

Immunogen

Synthesized peptide derived from human TAS2R38.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Predicted to react with Mouse and Rat samples
  • Receptor that may play a role in the perception of bitterness and is gustducin-linked
  • May play a role in sensing the chemical composition of the gastrointestinal content
  • The activity of this receptor may stimulate alpha gustducin, mediate PLC-beta-2 activation and lead to the gating of TRPM5
  • Expressed in subsets of taste receptor cells of the tongue and exclusively in gustducin-positive cells
  • Variations in TAS2R38 are associated with the ability to taste phenylthiocarbamide (PTC tasting); also called thiourea tasting
  • The ability to taste the substance PTC and a number of related substances is genetically controlled
  • Genetic studies have demonstrated complex inheritance for this trait
  • For some people (and some chimpanzees also), the chemical PTC tastes very bitter
  • For others, it is tasteless
  • Actually, substantial variation in taste sensitivity exists in human
  • Five haplotypes arising from three coding SNPs in the TAS2R38 gene are associated with distinct phenotypes of PTC taste sensitivity.