PIPA568177

HECW1 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA568177-Each-of-1 In Stock ₹ 46,057.50

PIPA568177 - Each of 1

₹ 46,057.50

In Stock

Quantity

1

Base Price: ₹ 46,057.50

GST (18%): ₹ 8,290.35

Total Price: ₹ 54,347.85

Antigen

HECW1

Classification

Polyclonal

Conjugate

Unconjugated

Gene

HECW1

Gene Alias

E3 ubiquitin-protein ligase HECW1; HECT type E3 ubiquitin ligase; HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1; HECT, C2 and WW domain-containing protein 1; HECT-type E3 ubiquitin transferase HECW1; HECW1; hNEDL1; KIAA0322; NEDD4-like E3 ubiquitin-protein ligase 1; NEDD4-like ubiquitin-protein ligase 1; NEDL1; RGD1561038

Host Species

Rabbit

Purification Method

affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

23072

Content And Storage

-20°C

Form

Liquid

Applications

Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.

Q76N89

Gene Symbols

HECW1

Immunogen

Synthesized peptide derived from human HECW1.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent degradation of DVL1
  • Also targets the mutant SOD1 protein involved in familial amyotrophic lateral sclerosis (FALS)
  • Forms cytotoxic aggregates with DVL1, SSR3 and mutant SOD1 that lead to motor neuron death in FALS.