COL11A1 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA568410-Each-of-1 | In Stock | ₹ 45,968.50 |
PIPA568410 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 45,968.50
GST (18%): ₹ 8,274.33
Total Price: ₹ 54,242.83
Antigen
COL11A1
Classification
Polyclonal
Conjugate
Unconjugated
Gene
COL11A1
Gene Alias
a1(XI) collagen; C530001D20Rik; cho; chondrodysplasia; CO11A1; COBA1; COL11A1; COLL6; Collagen alpha 1; collagen alpha-1(XI) chain; collagen type XI alpha 1 chain; collagen XI, alpha-1 polypeptide; collagen, type XI, alpha 1; pro-alpha1(XI) collagen; procollagen, type XI, alpha 1; STL2; STL3; XI chain precursor
Host Species
Rabbit
Purification Method
affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
1301
Content And Storage
-20°C
Form
Liquid
Applications
Immunohistochemistry (Paraffin)
Concentration
0.8 mg/mL
Formulation
PBS with 40% glycerol and 0.05% sodium azide; pH 7.4
Gene Accession No.
P12107
Gene Symbols
COL11A1
Immunogen
Synthetic protein corresponding to internal residues of human COL11A1.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Collagen Type XI is an 1806 amino acid protein belonging to the fibrillar collagen family
- Collagen Type XI is thought to play an important role in fibrillogenesis by controlling lateral growth of collagen II fibrils
- This protein forms trimers composed of three different chains: a 1(XI), a 2(XI), and a 3(XI)
- a 3(XI) is a post-translational modification of a 1(II)
- a 1(V) can also be found instead of a 3(XI)
- Collagen Type XI has three named isoforms (A,B,C) and additional isoforms seem to exist, stemming from alternative usage of exon IIA or exon IIB
- Transcripts containing exon IIA or IIB are present in cartilage, but exon IIB is preferentially utilized in transcripts from tendon
- Collagen Type XI contains a single collagen binding TSP N-terminal (TSPN) domain
- Collagen Type XI is expressed in cartilage, placenta and some tumor or virally transformed cell lines
- Isoform expression can be tissue specific
- Defects in the COL11A gene are the cause of Stickler syndrome type 2 (STL2), or beaded vitreous type, due to the presence of irregularly thickened fiber bundles throughout vitreous cavity.