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PIPA568434

CD153 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA568434-Each-of-1 In Stock ₹ 45,968.50

PIPA568434 - Each of 1

₹ 45,968.50

In Stock

Quantity

1

Base Price: ₹ 45,968.50

GST (18%): ₹ 8,274.33

Total Price: ₹ 54,242.83

Antigen

CD153

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Tnfsf8

Gene Alias

CD153; CD153 antigen; CD30 antigen ligand; CD30 ligand; Cd30l; CD30-L; Cd30lg; CD30ligand; Tnfsf8; TNLG3A; tumor necrosis factor (ligand) superfamily member 8; tumor necrosis factor (ligand) superfamily, member 8; tumor necrosis factor ligand 3A; tumor necrosis factor ligand superfamily member 8; tumor necrosis factor superfamily member 8

Host Species

Rabbit

Purification Method

affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

944

Content And Storage

-20°C

Form

Liquid

Applications

Immunohistochemistry (Paraffin)

Concentration

0.5 mg/mL

Formulation

PBS with 40% glycerol and 0.05% sodium azide; pH 7.4

Gene Accession No.

P32971

Gene Symbols

Tnfsf8

Immunogen

Synthetic peptide corresponding to residues near the N terminal of human TNFSF8.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

Description

  • The ligand for CD30 is CD30L (CD153)
  • The binding of CD30 to CD30L mediates pleiotropic effects including cell proliferation, activation, differentiation, and apoptotic cell death
  • CD30 has a critical role in the pathophysiology of Hodgkin's disease and other CD30+ lymphomas
  • CD30 acts as a costimulatory molecule in thymic negative selection
  • In addition to its expression on Hodgkin's and Reed-Sternberg cells, CD30 is also found in some non-Hodgkin's lymphomas (including Burkitt's lymphomas), virus-infected T and B cells, and on normal T and B cells after activation
  • In T cells, CD30 expression is present on a subset of T cells that produce Th2-type cytokines and on CD4+/CD8+ thymocytes that coexpress CD45RO and the IL4 receptor.