Cytokeratin 14/17 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA568451-Each-of-1 | In Stock | ₹ 46,502.50 |
PIPA568451 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,502.50
GST (18%): ₹ 8,370.45
Total Price: ₹ 54,872.95
Antigen
Cytokeratin 14/17
Classification
Polyclonal
Conjugate
Unconjugated
Gene
KRT14
Gene Alias
39.1; AI626930; CK14; CK-14; CK-17; cytokeratin 14; cytokeratin-14; Cytokeratin-17; EBS3; EBS4; epidermolysis bullosa simplex, Dowling-Meara, Koebner; K14; K17; Ka14; Ka17; keratin 14; keratin 14 (epidermolysis bullosa simplex, Dowling-Meara, Koebner); keratin 14, type I; keratin 17; keratin 17, type I; keratin complex 1, acidic, gene 14; keratin complex 1, acidic, gene 17; keratin, type I cytoskeletal 14; Keratin, type I cytoskeletal 17; keratin-14; Keratin-17; Krt-1.14; Krt1-14; Krt1-17; KRT14; KRT17; krt17 {ECO:0000250; LOC100737113; NFJ; PC; PC2; PCHC1; type I keratin Ka14; Type I keratin Ka17; UniProtKB:Q04695}
Host Species
Rabbit
Purification Method
affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
16664, 16667, 287701, 287702, 3861, 3872
Content And Storage
-20°C
Form
Liquid
Applications
Immunohistochemistry (Paraffin), Western Blot
Concentration
1 mg/mL
Formulation
PBS with 0.5% BSA, 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.
P02533, Q04695, Q61781, Q6IFU8, Q6IFV1, Q9QWL7
Gene Symbols
KRT14, KRT17
Immunogen
Synthesized peptide derived from human Cytokeratin 14/17 [aa 261-310].
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Predicted to react with Mouse and Rat samples
- Cytokeratins(CK) are intermediate filaments of epithelial cells, both in keratinizing tissue (ie
- Skin) and non-keratinizing cells (ie
- Mesothelial cells)
- Although not a traditional marker for endothelial cells, cytokeratins have also been found in some microvascular endothelial cells
- Atleast 20 different CKs in the molecular range of 40-70 k Da and isoelectric points of 5-805 can be identified using two dimensional gel electrophoresis
- Biochemically, most members of the CK family fall into one of two classes, type I (acidic polypeptides) and type II (basic polypeptides)
- At least one member of the acidic family and one member of the basic family is expressed in all epithelial cells
- Monoclonal antibodies to cytokeratin proteins can be useful markers for tumor identification and classification
- Belonging to the type A (acidic) subfamily of low molecular weight keratins and existing in combination with keratin 5, keratin 14 distinguishes stratified epithelial cells from simple epithelial cells and is useful in identification of squamous cell carcinomas
- It is considered a prognostic marker in breast carcinomas.