PIPA568791

TOB1 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA568791-Each-of-1 In Stock ₹ 46,057.50

PIPA568791 - Each of 1

₹ 46,057.50

In Stock

Quantity

1

Base Price: ₹ 46,057.50

GST (18%): ₹ 8,290.35

Total Price: ₹ 54,347.85

Antigen

TOB1

Classification

Polyclonal

Conjugate

Unconjugated

Gene

TOB1

Gene Alias

APRO5; APRO6; MGC104792; MGC34446; PIG49; proliferation-inducing gene 49; protein Tob1; Protein Tob1-like protein; TOB; TOB1; transducer of erbB2; Transducer of erbB-2 1; transducer of ERBB2, 1; transducer of ErbB-2.1; Trob; TROB1; Unknown (protein for MGC:134447)

Host Species

Rabbit

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

22057

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Western Blot

Concentration

1.0 mg/mL

Formulation

PBS with 2% sucrose and 0.09% sodium azide

Gene Accession No.

Q61471

Gene Symbols

TOB1

Immunogen

synthetic peptide directed towards the middle region of mouse TOB1

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Mouse

Product Type

Antibody

Isotype

IgG

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Description

  • This target displays homology in the following species: Cow: 93%; Dog: 93%; Horse: 93%; Human: 93%; Mouse: 100%; Pig: 93%; Rat: 93% This gene encodes a member of the tob/btg1 family of anti-proliferative proteins that have the potential to regulate cell growth
  • When exogenously expressed, this protein supresses cell growth in tissue culture
  • The protein undergoes phophorylation by a serine/threonine kinase, 90 kDa ribosomal S6 kinase
  • Interactions of this protein with the v-erb-b2 erythroblastic leukemia viral oncogene homolog 2 gene product p185 interferes with growth suppression
  • This protein inhibits T cell proliferation and transcription of cytokines and cyclins
  • The protein interacts with both mothers against decapentaplegic Drosophila homolog 2 and 4 to enhance their DNA binding activity
  • This interaction inhibits interleukin 2 transcription in T cells.