PAK4 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA569540-Each-of-1 | In Stock | ₹ 46,057.50 |
PIPA569540 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,057.50
GST (18%): ₹ 8,290.35
Total Price: ₹ 54,347.85
Antigen
PAK4
Classification
Polyclonal
Conjugate
Unconjugated
Gene
Pak4
Gene Alias
5730488L07Rik; AW555722; hypothetical protein LOC431769; im:5916170; Kiaa1142; mKIAA1142; p21 (CDKN1A)-activated kinase 4; p21 (RAC1) activated kinase 4; p21 protein (Cdc42/Rac)-activated kinase 4; p21(CDKN1A)-activated kinase 4; p21-activated kinase 4; Pak4; PAK-4; protein kinase related to S. cerevisiae STE20, effector for Cdc42Hs; serine/threonine-protein kinase PAK 4; wu:fd12b01; zgc:92014
Host Species
Rabbit
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
292756
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Western Blot
Concentration
0.5 mg/mL
Formulation
PBS with 2% sucrose and 0.09% sodium azide
Gene Accession No.
0
Gene Symbols
Pak4
Immunogen
synthetic peptide corresponding to a region of rat PAK4
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- This target displays homology in the following species: Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 79% PAK4 is a serine/ threonine p21 activating kinase implicated in the reorganization of actin cytoskeleton and in the formation of filopodia
- They are divided into two groups, the first of which include PAK1, 2 and 3, and can be activated by Cdc42/Rac binding
- The second group includes PAK4, 5 and 6
- These proteins are not activated by Cdc42/Rac binding
- PAK4 was initially identified as a novel effector of Cdc42Hs
- Co-expression of PAK4 and Cdc42Hs resulted in induction of filopodia and actin polymerization, showing that it is involved in cytoskeletal reorganization
- Other experiments have shown PAK4 to be essential for embryonic viability and proper neuronal development
- PAK4 has also been implicated in anchorage-independent growth of tumor cells and is required for activation of several cancer prosurvival pathways.