PTPN13 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA572907-Each-of-1 | In Stock | ₹ 46,502.50 |
PIPA572907 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,502.50
GST (18%): ₹ 8,370.45
Total Price: ₹ 54,872.95
Antigen
PTPN13
Classification
Polyclonal
Conjugate
Unconjugated
Gene
PTPN13
Gene Alias
AI324989; DKFZp686J1497; FAP-1; Fas-associated protein-tyrosine phosphatase 1; hPTP1E; hPTPE1; PNP1; protein Tyr phosphatase; protein tyrosine phosphatase DPZPTP; Protein tyrosine phosphatase PTP-BL; protein tyrosine phosphatase, non-receptor type 13; protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase); protein-tyrosine phosphatase 1E; Protein-tyrosine phosphatase PTPL1; protein-tyrosine phosphatase RIP; ptp; Ptp14; PTP1E; PTP36; PTP-BAS; PTP-BL; PTP-E1; PTPL1; PTPLE; PTPN13; Ptpri; RIP; tyrosine phosphatase; tyrosine-protein phosphatase non-receptor type 13
Host Species
Rabbit
Quantity
50 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Applications
Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Concentration
Conc. Not Determined
Formulation
whole serum with 0.02% sodium azide
Gene Accession No.
Q12923
Gene Symbols
PTPN13
Immunogen
A synthetic peptide corresponding to amino acids 1760-1775 of human FAP-1; GenBank no. NP_542414.1. This peptide sequence is conserved in multiple isoforms of FAP-1.
Regulatory Status
RUO
Gene ID (Entrez)
5783
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Related Products
Description
- The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family
- PTPs are signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation
- This PTP is a large intracellular protein
- It has a catalytic PTP domain at its C-terminus and two major structural domains: a region with five PDZ domains and a FERM domain that binds to plasma membrane and cytoskeletal elements
- This PTP was found to interact with, and dephosphorylate, Fas receptor and IkappaBalpha through the PDZ domains
- This suggests it has a role in Fas mediated programmed cell death
- This PTP was also shown to interact with GTPase-activating protein, and thus may function as a regulator of Rho signaling pathways
- Four alternatively spliced transcript variants, which encode distinct proteins, have been reported.