PIPA572970

FAT4 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA572970-Each-of-1 In Stock ₹ 46,057.50

PIPA572970 - Each of 1

₹ 46,057.50

In Stock

Quantity

1

Base Price: ₹ 46,057.50

GST (18%): ₹ 8,290.35

Total Price: ₹ 54,347.85

Antigen

FAT4

Classification

Polyclonal

Conjugate

Unconjugated

Gene

FAT4

Gene Alias

6030410K14Rik; 9430004M15; Cadherin family member 14; cadherin-related family member 11; CDHF14; CDHR11; FAT atypical cadherin 4; FAT tumor suppressor homolog 4; FAT tumor suppressor homolog 4 (Drosophila); FAT4; Fatj; FAT-J; fat-like cadherin protein FAT-J; hFat4; HKLLS2; Nbla00548; protocadherin Fat 4; putative protein product of Nbla00548; RGD1564291; VMLDS2

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

329628, 79633

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration

1.0 mg/mL

Formulation

PBS with 30% glycerol and 0.05% sodium azide

Gene Accession No.

Q2PZL6, Q6V0I7

Gene Symbols

FAT4

Immunogen

A synthetic peptide made to a C-terminal portion of the human FAT4 protein (between residues 4000-4500) [UniProt Q6V0I7]

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG

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Description

  • FAT1, FAT2, FAT3 and FAT4 are human homologs of Drosophila Fat, which is involved in tumor suppression and planar cell polarity (PCP)
  • FAT4 undergo the first proteolytic cleavage by Furin and are predicted to undergo the second cleavage by secretase to release intracellular domain (ICD)
  • FAT4 directly interacts with MPDZ/MUPP1 to recruit membrane associated guanylate kinase MPP5/PALS1
  • FAT4 is involved in the maintenance of PCP and inhibition of cell proliferation.