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PIPA575225

ATF7 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA575225-Each-of-1 In Stock ₹ 46,502.50

PIPA575225 - Each of 1

₹ 46,502.50

In Stock

Quantity

1

Base Price: ₹ 46,502.50

GST (18%): ₹ 8,370.45

Total Price: ₹ 54,872.95

Antigen

ATF7

Classification

Polyclonal

Conjugate

Unconjugated

Gene

ATF7

Gene Alias

1110012F10Rik; 9430065F09Rik; activating transcription factor 7; AI549878; ATF7; ATFA; C130020M04Rik; cAMP-dependent transcription factor ATF-7; Cyclic AMP-dependent transcription factor ATF-7; MGC57182; transcription factor ATF-A

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

11016, 223922, 315333

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration

1 mg/mL

Formulation

PBS with 0.05% sodium azide; pH 7.2

Gene Accession No.

P17544, Q8R0S1

Gene Symbols

ATF7

Immunogen

Synthetic peptide corresponding to amino acids 40-90 of Human ATF7.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

Description

  • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE)
  • Plays important functions in early cell signaling
  • Binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AG][AG]-3'), a sequence present in many viral and cellular promoters
  • Activator of the NF-ELAM1/delta-A site of the E-selectin promoter
  • Has no intrinsic transcriptional activity, but activates transcription on formation of JUN or FOS heterodimers
  • Also can bind TRE promoter sequences when heterodimerized with members of the JUN family
  • Isoform 4/ATF-A0acts as a dominant repressor of the E-selectin/NF-ELAM1/delta-A promoter
  • Isoform 5/ATF-4acts as a negative regulator, inhibiting both ATF2 and ATF7 transcriptional activities
  • It may exert these effects by sequestrating in the cytoplasm the Thr-53 phosphorylating kinase, preventing activation.