PIPA575268

COX11 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA575268-Each-of-1 In Stock ₹ 46,502.50

PIPA575268 - Each of 1

₹ 46,502.50

In Stock

Quantity

1

Base Price: ₹ 46,502.50

GST (18%): ₹ 8,370.45

Total Price: ₹ 54,872.95

Antigen

COX11

Classification

Polyclonal

Conjugate

Unconjugated

Gene

COX11

Gene Alias

2010004I09Rik; Cox11; COX11 cytochrome c oxidase copper chaperone; COX11 homolog, cytochrome c oxidase assembly protein; COX11, cytochrome c oxidase copper chaperone; COX11P; cytochrome c oxidase assembly homolog 11; cytochrome c oxidase assembly protein 11; cytochrome c oxidase assembly protein COX11, mitochondrial; cytochrome c oxidase subunit 11

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

1353, 690300, 69802

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunohistochemistry (Paraffin)

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.

Q6P8I6, Q9Y6N1

Gene Symbols

COX11

Immunogen

Synthetic peptide corresponding to amino acids 50-100 of Human COX11.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE)
  • Cytochrome c oxidase (COX) is the terminal enzyme in the electron transfer chain, functioning as a transmembrane proton pump that builds an electrochemical gradient with chemical energy from the reduction of O2
  • Cytochrome c oxidase assembly protein COX11 is an intracellular mitochondrial membrane protein necessary for the construction of an active COX complex
  • COX11 contains a single transmembrane helix downstream of the N-terminal, mitochondrial targeting sequence and a C-terminal Cu(I)-binding domain
  • The assembly of COX requires the delivery of metal cofactors
  • Along with COX12 and SCO1/2, COX11 acts as a metal ion chaperone necessary for copper insertion into CuA and CuB redox-active copper centers of COX in eukaryotes.