PIPA575527

KCNH1 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA575527-Each-of-1 In Stock ₹ 46,502.50

PIPA575527 - Each of 1

₹ 46,502.50

In Stock

Quantity

1

Base Price: ₹ 46,502.50

GST (18%): ₹ 8,370.45

Total Price: ₹ 54,872.95

Antigen

KCNH1

Classification

Polyclonal

Conjugate

Unconjugated

Gene

KCNH1

Gene Alias

EAG; EAG channel 1; EAG1; ether a go-go; ether-a-go-go potassium channel 1; ether-a-go-go, Drosophila, homolog of; h-eag; hEAG1; Kcnh1; Kv10.1; M-eag; potassium channel, voltage gated eag related subfamily H, member 1; potassium voltage-gated channel subfamily H member 1; potassium voltage-gated channel, subfamily H (eag-related), member 1; r-eag; TMBTS; voltage-gated potassium channel subunit Kv10.1; ZLS1

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

16510, 3756, 65198

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.

O95259, Q60603, Q63472

Gene Symbols

KCNH1

Immunogen

Synthetic peptide corresponding to amino acids 762-807 of Human KCNH1.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE)
  • Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints
  • Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume
  • KCNH1 encodes a member of the potassium channel, voltage-gated, subfamily H
  • This member is a pore-forming (alpha) subunit of a voltage-gated non-inactivating delayed rectifier potassium channel
  • KCNH1 is activated at the onset of myoblast differentiation
  • KCNH1 is highly expressed in brain and in myoblasts
  • Overexpression of KCNH1 may confer a growth advantage to cancer cells and favor tumor cell proliferation
  • Alternative splicing of KCNH1 results in two transcript variants encoding distinct isoforms.