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PIPA577950

E2F2 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIPA577950-Each-of-1 In Stock ₹ 48,905.50

PIPA577950 - Each of 1

₹ 48,905.50

In Stock

Quantity

1

Base Price: ₹ 48,905.50

GST (18%): ₹ 8,802.99

Total Price: ₹ 57,708.49

Antigen

E2F2

Classification

Polyclonal

Conjugate

Unconjugated

Gene

E2F2

Gene Alias

E2F transcription factor 2; E2F2; E2F-2; LOW QUALITY PROTEIN: transcription factor E2F2; transcription factor E2F2

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

1870

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunocytochemistry, Western Blot

Concentration

1.93 mg/mL

Formulation

PBS with 20% glycerol and 0.025% ProClin 300; pH 7

Gene Accession No.

Q14209

Gene Symbols

E2F2

Immunogen

Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of human E2F2. The exact sequence is proprietary.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

Description

  • Positive Control: 293T, 293T nuclear extract, K562, K562 nuclear extract Store product as a concentrated solution
  • Centrifuge briefly prior to opening the vial
  • E2F2 is a member of the E2Ffamily of transcription factors
  • The E2F family plays a crucialrole in the control of cell cycle and action of tumor suppressorproteins and is also a target of the transforming proteins of smallDNA tumor viruses
  • The E2F proteins contain several evolutionallyconserved domains found in most members of the family
  • Thesedomains include a DNA binding domain, a dimerization domain whichdetermines interaction with the differentiation regulatedtranscription factor proteins (DP), a transactivation domainenriched in acidic amino acids, and a tumor suppressor proteinassociation domain which is embedded within the transactivationdomain
  • This protein and another 2 members, E2F1 and E2F3, have anadditional cyclin binding domain
  • This protein binds specificallyto retinoblastoma protein pRB in a cell-cycle dependent manner, andit exhibits overall 46% amino acid identity to E2F1.