PIPA578075

NeuroD1 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA578075-Each-of-1 In Stock ₹ 48,905.50

PIPA578075 - Each of 1

₹ 48,905.50

In Stock

Quantity

1

Base Price: ₹ 48,905.50

GST (18%): ₹ 8,802.99

Total Price: ₹ 57,708.49

Antigen

NeuroD1

Classification

Polyclonal

Conjugate

Unconjugated

Gene

NEUROD1

Gene Alias

Basic helix-loop-helix factor 1; basic helix-loop-helix transcription factor; Beta2; beta-cell E-box transactivator 2; beta-cell E-box transcriptional activator 2; BHF1; BHF-1; bHLHa3; Class A basic helix-loop-helix protein 3; MODY6; neuro d1; Neurod; Neurod1; neurogenic differentiation 1; neurogenic differentiation factor 1; neurogenic helix-loop-helix protein NEUROD; neuronal differentiation 1

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

18012, 29458, 4760

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

ChIP Assay, Immunocytochemistry, Immunohistochemistry (Frozen), Western Blot

Concentration

0.47 mg/mL

Formulation

PBS with 1% BSA, 20% glycerol and 0.025% ProClin 300; pH 7

Gene Accession No.

Q13562, Q60867, Q64289

Gene Symbols

NEUROD1

Immunogen

Carrier-protein conjugated synthetic peptide encompassing a sequence within the center region of mouse NeuroD1. The exact sequence is proprietary.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Positive Control: IMR32, IMR32 nuclear extract Predicted Reactivity: Mouse (100%), Bovine (100%) Store product as a concentrated solution
  • Centrifuge briefly prior to opening the vial
  • NeuroD1 is a transcriptional activator that acts as a differentiation factor during neurogenesis
  • It has been demonstrated to bind to the insulin gene E-box
  • Efficient DNA binding requires dimerization with another basic helix-loop-helix (bHLH) protein
  • Defects in NEUROD1 are a cause of maturity onset diabetes of the young type VI (MODY6)
  • MODY6 is a form of non-insulin-dependent diabetes mellitus characterized by an autosomal dominant mode of inheritance, onset during young adulthood and a primary defect in insulin secretion.