PIPA578123

PRKAR2A Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA578123-Each-of-1 In Stock ₹ 49,439.50

PIPA578123 - Each of 1

₹ 49,439.50

In Stock

Quantity

1

Base Price: ₹ 49,439.50

GST (18%): ₹ 8,899.11

Total Price: ₹ 58,338.61

Antigen

PRKAR2A

Classification

Polyclonal

Conjugate

Unconjugated

Gene

PRKAR2A

Gene Alias

1110061A24Rik; AI317181; AI836829; cAMP-dependent protein kinase regulatory subunit RII alpha; cAMP-dependent protein kinase type II-alpha regulatory subunit; cAMP-dependent protein kinase, regulatory subunit alpha 2; MGC3606; PKR2; PRKAR2; Prkar2a; protein kinase A, RII-alpha subunit; protein kinase cAMP-dependent regulatory type II alpha; protein kinase cAMP-dependent type II regulatory subunit alpha; protein kinase, cAMP dependent regulatory, type II alpha; protein kinase, cAMP-dependent, regulatory subunit type II alpha; protein kinase, cAMP-dependent, regulatory, type 2, alpha; protein kinase, cAMP-dependent, regulatory, type II, alpha; RII(alpha); unnamed protein product

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

5576

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunocytochemistry, Western Blot

Concentration

1.0 mg/mL

Formulation

PBS with 20% glycerol and 0.01% thimerosal; pH 7

Gene Accession No.

P13861

Gene Symbols

PRKAR2A

Immunogen

Recombinant protein encompassing a sequence within the center region of human PKA R2. The exact sequence is proprietary.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • Positive Control: 293T, A431, HeLa, HepG2 Predicted Reactivity: Mouse (95%), Rat (95%), Pig (97%), Chimpanzee (99%), Bovine (96%) Store product as a concentrated solution
  • Centrifuge briefly prior to opening the vial
  • cAMP is a signaling molecule important for a variety of cellular functions
  • cAMP exerts its effects by activating the cAMP-dependent protein kinase (AMPK), which transduces the signal through phosphorylation of different target proteins
  • The inactive holoenzyme of AMPK is a tetramer composed of two regulatory and two catalytic subunits
  • cAMP causes the dissociation of the inactive holoenzyme into a dimer of regulatory subunits bound to four cAMP and two free monomeric catalytic subunits
  • Four different regulatory subunits and three catalytic subunits of AMPK have been identified in humans
  • The protein encoded by this gene is one of the regulatory subunits
  • This subunit can be phosphorylated by the activated catalytic subunit
  • It may interact with various A-kinase anchoring proteins and determine the subcellular localization of AMPK.