ZEB2 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA578302-Each-of-1 | In Stock | ₹ 49,439.50 |
PIPA578302 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 49,439.50
GST (18%): ₹ 8,899.11
Total Price: ₹ 58,338.61
Antigen
ZEB2
Classification
Polyclonal
Conjugate
Unconjugated
Gene
Zeb2
Gene Alias
9130203F04Rik; D130016B08Rik; HRIHFB2411; HSPC082; KIAA0569; SIP1; SIP-1; SMAD interacting protein 1; smad-interacting protein 1; SMADIP1; Zeb2; ZFHX1B; Zfx1b; Zfxh1b; zinc finger E-box binding homeobox 2; zinc finger E-box-binding homeobox 2; zinc finger homeobox 1b; zinc finger homeobox protein 1b
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
24136, 9839
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration
0.42 mg/mL
Formulation
PBS with 1% BSA, 20% glycerol and 0.025% ProClin 300; pH 7
Gene Accession No.
O60315, Q9R0G7
Gene Symbols
Zeb2
Immunogen
Recombinant protein encompassing a sequence within the center region of human ZEB2. The exact sequence is proprietary.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Positive Control: MEF, A375, Neuro 2A, C8D30, Raw264.7, C2C12, rat brain Predicted Reactivity: Xenopus laevis (87%), Chicken (93%) Store product as a concentrated solution
- Centrifuge briefly prior to opening the vial
- ZEB2, initially identified as Smad interacting-protein 1, is normally located in the nucleus and functions as a DNA-binding transcriptional repressor that interacts with activated SMADs
- Like the homologous ZEB1, ZEB2 inhibits the transcription of the E-cadherin gene and induces epithelial-mesenchymal transition, a genetic program controlling cell migration during embryonic development and wound healing, in vitro
- ZEB2 can also protect cells from DNA damage-induced apoptosis, suggesting that its expression may contribute to tumor progression
- Recent evidence has shown that ZEB2 is often observed in the cytoplasm in numerous cancer tissues, indicating that its localization may be regulated in normal and tumor tissues
- Mutations in this gene are also associated with Hirschsprung disease/Mowat-Wilson syndrome.