Home Products Antibodies Primary Antibodies PIPA578329
PIPA578329

NOP56 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA578329-Each-of-1 In Stock ₹ 49,439.50

PIPA578329 - Each of 1

₹ 49,439.50

In Stock

Quantity

1

Base Price: ₹ 49,439.50

GST (18%): ₹ 8,899.11

Total Price: ₹ 58,338.61

Antigen

NOP56

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Nop56

Gene Alias

2310044F10Rik; 56kDa with KKE/D repeat; hypothetical protein 1195; NOL5A; Nop56; NOP56 ribonucleoprotein; NOP56 ribonucleoprotein homolog; nucleolar protein 56; Nucleolar protein 5A; nucleolar protein 5A (56kDa with KKE/D repeat); SCA36; similar to nucleolar protein 5A (56kDa with KKE/D repeat)

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

10528

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Concentration

0.54 mg/mL

Formulation

PBS with 20% glycerol and 0.025% ProClin 300; pH 7

Gene Accession No.

O00567

Gene Symbols

Nop56

Immunogen

Recombinant protein encompassing a sequence within the C-terminus of human NOL5A. The exact sequence is proprietary.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

Description

  • Positive Control: 293T, A431, HeLa, HepG2 Predicted Reactivity: Chimpanzee (95%) Store product as a concentrated solution
  • Centrifuge briefly prior to opening the vial
  • ErbB 4 (Her-4, c-erbB-4, v-erbB-4) is a member of the class I receptor kinase family
  • With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes
  • The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains
  • ErbB 4 is activated by neuregulins and NTAK (neural and thymus derived activator for ErbB kinases)
  • ErbB 4 is a receptor for heregulin and is capable of mediating HGL-stimulated tyrosine phosphorylation of itself
  • Like other protein kinases, ErbB 4 mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation
  • ErbB 4 is most predominantly expressed in several breast carcinoma cell lines, and in normal skeletal muscle, heart, pituitary, brain, and cerebellum
  • Breast tumor cell lines T47-D, MDA-MB-453, BT-474 and H3396 are found to have the highest levels of mRNA, and intermediate levels are seen in MCF-7, MDAMB-330 and MDA-MB-361
  • Expression of ErbB 4 is low or absent in some breast tumor cell lines such as MDA-MB-231, MDA-MB-157, MDA-MB-468, and SKBR-3
  • ErbB 4 levels have been found to be elevated in certain human tumor cell lines suggesting that it may play a role in some malignancies.