LAMTOR1 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA578516-Each-of-1 | In Stock | ₹ 48,905.50 |
PIPA578516 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 48,905.50
GST (18%): ₹ 8,802.99
Total Price: ₹ 57,708.49
Antigen
LAMTOR1
Classification
Polyclonal
Conjugate
Unconjugated
Gene
LAMTOR1
Gene Alias
2400001E08Rik; C11orf59; Lamtor1; Late endosomal/lysosomal adaptor and MAPK and MTOR activator 1; late endosomal/lysosomal adaptor, MAPK and MTOR activator 1; lipid raft adaptor protein p18; p18; p27kip1 releasing factor from RhoA; p27Kip1-releasing factor from RhoA; p27RF Rho; p27RF-Rho; Pdro; PP7157; Protein associated with DRMs and endosomes; ragulator complex protein LAMTOR1; ragulator complex protein PDRO; Ragulator1; RhoA activator C11orf59; RhoA activator C11orf59 homolog
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
55004, 66508
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Immunocytochemistry, Western Blot
Concentration
0.69 mg/mL
Formulation
PBS with 20% glycerol and 0.025% ProClin 300; pH 7
Gene Accession No.
Q6IAA8, Q9CQ22
Gene Symbols
LAMTOR1
Immunogen
Full length human LAMTOR1 recombinant protein.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Positive Control: HeLa, SKNSH Predicted Reactivity: Mouse (99%), Rat (97%), Rhesus Monkey (100%), Bovine (99%) Store product as a concentrated solution
- Centrifuge briefly prior to opening the vial
- The Ragulator complex is comprised of three proteins, C11orf59, ROBLD3, and MAPKSP1, which targets mTORC1 to lysosomal surfaces
- This normal endosomal trafficking is taken advantage of by certain viruses, including coronavirus, which has increased replication when C11orf59 is interfered with
- C11orf59 is positively regulated by cellular cholesterol depletion and negatively regulated by cellular cholesterol loading
- It is involved in LDL uptake and cholesterol homeostasis
- C11orf59 and PPAR-alpha work together to control lipid and carbohydrate metabolism in diabetes
- Nearly all effects of C11orf59 are associated with mTORC1 kinase growth promotion, and disregulation of the normal mTOR pathway.