EFHD2 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA578575-Each-of-1 | In Stock | ₹ 49,261.50 |
PIPA578575 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 49,261.50
GST (18%): ₹ 8,867.07
Total Price: ₹ 58,128.57
Antigen
EFHD2
Classification
Polyclonal
Conjugate
Unconjugated
Gene
Efhd2
Gene Alias
2600015J22Rik; AA408606; D4Wsu27e; EF hand domain containing 2; EF hand domain family, member D2; EF-hand domain family member D2; EF-hand domain family, member D2; EF-hand domain-containing protein D2; Efhd2; MGC4342; RP3-467K16.3; swiprosin 1; swiprosin-1; Sws1; testicular tissue protein Li 62
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
27984, 298609, 79180
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Immunocytochemistry, Immunohistochemistry (Frozen), Western Blot
Concentration
0.2 mg/mL
Formulation
0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
Gene Accession No.
Q4FZY0, Q96C19, Q9D8Y0
Gene Symbols
Efhd2
Immunogen
Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human EFHD2. The exact sequence is proprietary.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Positive Control: H1299, HeLaS3, mouse brain, rat brain Predicted Reactivity: Rhesus Monkey (100%), Bovine (100%) Store product as a concentrated solution
- Centrifuge briefly prior to opening the vial
- EFHD2, also known as Swiprosin-1 or SWS1, is an EF-hand and coiled-coil-containing adaptor protein that plays a role in lymphocyte physiology
- EFHD2 exhibits the highest expression in CD8+ T cells and immature B cells
- It provides a membrane scaffold that is required for the Syk-, SLP-65-, and PLC-gamma2-dependent B-cell receptor (BCR)-induced calcium flux
- EFHD2 may also regulate BCR-induced immature and primary B-cell apoptosis
- It controls spontaneous apoptosis through the regulation of BCL2L1 abundance
- Also, EFHD2 plays a role as negative regulator of the canonical NF-kappa-B-activating branch.