PIPA582323
Thyroid Peroxidase Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA582323-Each-of-1 | In Stock | ₹ 52,332.00 |
PIPA582323 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 52,332.00
GST (18%): ₹ 9,419.76
Total Price: ₹ 61,751.76
Antigen
Thyroid Peroxidase
Classification
Polyclonal
Conjugate
Unconjugated
Gene
TPO
Gene Alias
EC 1.11.1; LOW QUALITY PROTEIN: thyroid peroxidase; MSA; TDH2A; thyroid microsomal antigen; thyroid peroxidase; thyroid peroxidase (332 AA); thyroperoxidase; TPO; TPX; TPXEC 1.11.1.8
Host Species
Rabbit
Purification Method
Anitgen affinity chromatography, Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
7173
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Immunohistochemistry
Concentration
0.1 mg/mL
Formulation
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.
P07202
Gene Symbols
TPO
Immunogen
Recombinant protein corresponding to Human TPO
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Immunogen sequence: RELEKHSLSR VICDNTGLTR VPMDAFQVGK FPEDFESCDS ITGMNLEAWR ETFPQDDKCG FPESVENGDF VHCEESGRRV LVYSCRHGYE LQGREQLTCT QEGWDFQPPL CKDVNECADG A Thyroid Peroxidase is a gene that encodes for a membrane-bound glycoprotein, which functions as an enzyme and plays a crucial role in the proper functioning of the thyroid gland
- This protein is responsible for the iodination of tyrosine residues in thyroglobulin and the formation of phenoxy-ester between pairs of iodinated tyrosines, which leads to the production of thyroid hormones such as thyroxine and triiodothyronine
- Mutations in this gene are known to cause several disorders related to thyroid hormone production, including congenital hypothyroidism, congenital goiter, and thyroid hormone organification defect IIA
- Several transcript variants encoding distinct isoforms have been identified for this gene, but the full-length nature of some variants remains undetermined
- Diseases associated with TPO include Thyroid Dyshormonogenesis 2A and Congenital Hypothyroidism.