B7-H3 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA582384-Each-of-1 | In Stock | ₹ 53,400.00 |
PIPA582384 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 53,400.00
GST (18%): ₹ 9,612.00
Total Price: ₹ 63,012.00
Antigen
B7-H3
Classification
Polyclonal
Conjugate
Unconjugated
Gene
CD276
Gene Alias
4Ig-B7-H3; 6030411F23Rik; AU016588; B7 homolog 3; B7h3; B7-H3; B7RP-2; CD276; CD276 antigen; CD276 molecule; CD276 molecule tv1; costimulatory molecule; PSEC0249; sB7 H3; sB7H3; sCD276; soluble B7 H3; soluble B7H3; soluble CD276; UNQ309/PRO352
Host Species
Rabbit
Purification Method
Anitgen affinity chromatography, Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
80381
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Immunohistochemistry, Western Blot
Concentration
0.1 mg/mL
Formulation
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.
Q5ZPR3
Gene Symbols
CD276
Immunogen
Recombinant protein corresponding to Human CD276
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Immunogen sequence: YSKPSMTLEP NKDLRPGDTV TITCSSYRGY PEAEVFWQDG QGVPLTGNVT TSQMANEQGL FDVHSVLRVV LGANGTYSCL VRNPVLQQDA HGSVTITGQP CD276 is a member of the B7 family of co-stimulatory molecules also known as B7-H3
- CD276 is a type I transmembrane protein that induces the proliferation of CD4+ and CD8+ T cells, enhances the generation of cytotoxic T cells and selectively stimulates the production of interferon gamma
- Expression of CD276 can be induced on dendritic cells and monocytes by inflammatory cytokines, and is also widely expressed in peripheral tissues including the heart, kidney, testis and colon
- In humans, CD276 exists as two isoforms which result from gene duplication and differential splicing
- CD276 is reported to have therapeutic potential for the regulation of cell-mediated immune responses to cancer, particularly in conjunction with anti-angiogenic therapy.