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PIPA582490

CD223 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA582490-Each-of-1 In Stock ₹ 51,397.50

PIPA582490 - Each of 1

₹ 51,397.50

In Stock

Quantity

1

Base Price: ₹ 51,397.50

GST (18%): ₹ 9,251.55

Total Price: ₹ 60,649.05

Antigen

CD223

Classification

Polyclonal

Conjugate

Unconjugated

Gene

LAG3

Gene Alias

Activation-induced cytidine deaminase-linked autoimmunity protein; Aida; CD223; FDC; LAG3; LAG-3; Ly66; lymphocyte activating 3; lymphocyte activation gene 3 protein; lymphocyte-activation gene 3; Secreted lymphocyte activation gene 3 protein; sLAG 3; sLAG3; sLAG-3; soluble LAG 3lymphocyte activating 3; soluble LAG3

Host Species

Rabbit

Purification Method

Anitgen affinity chromatography, Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

3902

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunohistochemistry

Concentration

0.2 mg/mL

Formulation

PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.

P18627

Gene Symbols

LAG3

Immunogen

Recombinant protein corresponding to Human LAG3

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

Description

  • Immunogen sequence: LVTGDNGDFT LRLEDVSQAQ AGTYTCHIHL QEQQLNATVT LAIITVTPKS FGSPGSLGKL LCEVTPVSGQ ERFVWSSLDT PSQRSFSGPW LEAQEAQLLS QPWQCQLYQG ERLLGAAVYF TELSSPGAQ LAG-3 is a 70-kDa surface glycoprotein belonging to the Ig superfamily with homology to CD4
  • LAG-3 binds to MHC class II with higher affinity than CD4 and is thought to be involved in the negative regulation of T cell activation and homeostatic proliferation
  • Surface expression of LAG-3 has been reported on activated T cells (including regulatory T cells) and NK cells
  • CD8+ T cells usually express LAG-3 at significantly higher levels than CD4+ T cells
  • Coexpression of LAG-3 and CD49b has been proposed to identify human and mouse Type 1 regulatory T cells (Tr1 cells).