CALM Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA582661-Each-of-1 | In Stock | ₹ 53,400.00 |
PIPA582661 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 53,400.00
GST (18%): ₹ 9,612.00
Total Price: ₹ 63,012.00
Antigen
CALM
Classification
Polyclonal
Conjugate
Unconjugated
Gene
Picalm
Gene Alias
CALM; Clathrin assembly lymphoid myeloid leukemia; clathrin assembly lymphoid myeloid leukemia protein; clathrin-assembly lymphoid leukemia protein; clathrin-assembly lymphoid myeloid leukemia protein; CLTH; fit1; fit-1; LAP; mKIAA4114; PAP180; phosphatidylinositol binding clathrin assembly protein; phosphatidylinositol-binding clathrin assembly protein; PICALM; rCALM
Host Species
Rabbit
Purification Method
Anitgen affinity chromatography, Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
233489, 8301, 89816
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Immunohistochemistry, Western Blot
Concentration
0.2 mg/mL
Formulation
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.
O55012, Q13492, Q7M6Y3
Gene Symbols
Picalm
Immunogen
Recombinant protein corresponding to Human PICALM
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Immunogen sequence: DIPDLSQAPS SLLDALEQHL ASLEGKKIKD STAASRATTL SNAVSSLAST GLSLTKVDER EKQAALEEEQ ARLKALKEQR L PICALM, also known as the clathrin assembly lymphoid myeloid leukemia (CALM) protein, co-localizes with clathrin at clathrin-coated areas of the plasma membrane and in the Golgi area, and is thought to be an important component of the coated pit internalization machinery
- Fusion proteins involving PICALM have been implicated in acute myeloid and T-cell acute lymphoblastic leukemia
- PICALM is also expressed in neurons and is present at the synapse where it facilitates the endocytosis of the synaptic vesicle protein VAMP2
- Recent studies have identified variants of PICALM associated with Alzheimer's disease and have suggested this protein may play a role in the endocytosis and recycling of the amyloid protein precursor (APP).