GAS2L1 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA582704-Each-of-1 | In Stock | ₹ 48,905.50 |
PIPA582704 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 48,905.50
GST (18%): ₹ 8,802.99
Total Price: ₹ 57,708.49
Antigen
GAS2L1
Classification
Polyclonal
Conjugate
Unconjugated
Gene
GAS2L1
Gene Alias
4930500E24Rik; D0Jmb1; Gar22; GAS2L1; GAS2-like protein 1; GAS2-related protein; GAS2-related protein on chromosome 22; growth arrest specific 2 like 1; growth arrest-specific 2 like 1; growth arrest-specific protein 2-like 1; TU-71.1
Host Species
Rabbit
Purification Method
Anitgen affinity chromatography, Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
10634, 360973, 78926
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Immunocytochemistry, Immunohistochemistry, Western Blot
Concentration
0.6 mg/mL
Formulation
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.
Q8JZP9, Q99501
Gene Symbols
GAS2L1
Immunogen
Recombinant protein corresponding to Human GAS2L1
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Immunogen sequence: RLSRVSSPSP ELGTTPASIF RTPLQLDPQQ EQQLFRRLEE EFLANARALE AVASVTPTGP APDPARAPDP PAPDSAYCSS SSSSSSLSVL GGKCG The Gas2 protein is thought to play a role in apoptosis by acting as a cell death substrate for caspases
- Gas2, a component of the microfilament system, is cleaved by a caspase (caspase-3 or caspase-7) at Asparagine 278 during apoptosis
- The cleaved form of Gas2 dramatically induces the re-arrangement of the Actin cytoskeleton and causes potent changes in the shape of the affected cells
- Gas2 is a cytoskeleton and peripheral membrane protein that co-localizes with Actin fibers at the cell border and along the stress fibers in growth-arrested fibroblasts
- Gas2 is mainly membrane-associated, but when hyperphosphorylated it will accumulate at membrane ruffles, indicating Gas2 involvement in that process
- Gar22 (Gas2-related protein on chromosome 22), also designated growth arrest-specific protein 2-like 1 (Gas2-like1), belongs to the Gas2 family and contains one CH (calponinhomo-logy) domain
- It is thought to be involved in the cross-linking of microtubules and microfilaments.