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PIPA584375

ARS2 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA584375-Each-of-1 In Stock ₹ 48,905.50

PIPA584375 - Each of 1

₹ 48,905.50

In Stock

Quantity

1

Base Price: ₹ 48,905.50

GST (18%): ₹ 8,802.99

Total Price: ₹ 57,708.49

Antigen

ARS2

Classification

Polyclonal

Conjugate

Unconjugated

Gene

SRRT

Gene Alias

2810019G02Rik, Ars2, arsenate resistance protein 2, arsenate resistance protein ARS2, arsenite resistance protein, arsenite resistance protein 2, arsenite-resistance protein 2, Asr2, ASR2A, ASR2B, ASR2C, ASR2D, ch211-283g2.4, CHUNP6881, LOC686980, serrate, Serrate RNA effector molecule homolog, serrate RNA effector molecule homolog (Arabidopsis), serrate, RNA effector molecule, similar to arsenate resistance protein 2, srrt, zgc:92060

Host Species

Rabbit

Purification Method

Anitgen affinity chromatography, Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

51593

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunocytochemistry, Western Blot, Western Blot

Concentration

0.05 mg/mL

Formulation

PBS with 40% glycerol and 0.02% sodium azide, pH 7.2

Gene Accession No.

Q9BXP5

Gene Symbols

SRRT

Immunogen

Recombinant protein corresponding to Human SRRT

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

Description

  • Immunogen sequence: GLTPGLPYPH QTPQGLMPYG QPRPPILGYG AGAVRPAVPT GGPPYPHAPY GAGRGNYDAF RGQGGYPGKP RNRMVRGDPR AIVEYRDLDA PDDVDFF Acts as a mediator between the cap-binding complex (CBC) and the primary microRNAs (miRNAs) processing machinery during cell proliferation
  • Contributes to the stability and delivery of capped primary miRNA transcripts to the primary miRNA processing complex containing DGCR8 and DROSHA, thereby playing a role in RNA-mediated gene silencing (RNAi) by miRNAs
  • Binds capped RNAs (m7GpppG-capped RNA); however interaction is probably mediated via its interaction with NCBP1/CBP80 component of the CBC complex
  • Involved in cell cycle progression at S phase
  • Does not directly confer arsenite resistance but rather modulates arsenic sensitivity
  • Independently of its activity on miRNAs, necessary and sufficient to promote neural stem cell self-renewal
  • Does so by directly binding SOX2 promoter and positively regulating its transcription
  • [UniProt]