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PIPA584948

PTRF Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA584948-Each-of-1 In Stock ₹ 48,905.50

PIPA584948 - Each of 1

₹ 48,905.50

In Stock

Quantity

1

Base Price: ₹ 48,905.50

GST (18%): ₹ 8,802.99

Total Price: ₹ 57,708.49

Antigen

PTRF

Classification

Polyclonal

Conjugate

Unconjugated

Gene

CAVIN1

Gene Alias

2310075E07Rik; AW546441; caveolae associated protein 1; caveolae-associated protein 1; CAVIN; CAVIN1; cavin-1; Cav-p60; CGL4; FKSG13; FLJ90031; Polymerase I and transcript release factor; PTRF; ptrf {ECO:0000312; RGD:1307685}; RNA polymerase I and transcript release factor; TTF-I interacting peptide 12

Host Species

Rabbit

Purification Method

Anitgen affinity chromatography, Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

284119

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunocytochemistry

Concentration

0.2 mg/mL

Formulation

PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.

Q6NZI2

Gene Symbols

CAVIN1

Immunogen

Recombinant protein corresponding to Human CAVIN1

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

Description

  • Immunogen sequence: VSVNVKTVRG SLERQAGQIK KLEVNEAELL RRRNFKVMIY QDEVKLPAKL SISKSLKESE ALPEKEGEEL GEGERPEEDA AALELSSD The polymerase I and transcript release factor (PTRF) enables the dissociation of paused ternary polymerase I transcription complexes from the 3' end of pre-rRNA transcripts, regulating rRNA transcription by promoting the dissociation of transcription complexes and the re-initiation of polymerase I on nascent rRNA transcripts
  • PTRF also localizes to caveolae at the plasma membrane and is thought to play a critical role in the formation of caveolae and the stabilization of caveolins, translocating from caveolae to the cytoplasm after insulin stimulation
  • PTRF is also thought to modify lipid metabolism and insulin-regulated gene expression
  • Mutations in this gene result in a disorder characterized by generalized lipodystrophy and muscular dystrophy.