PIPA585516
5-Methylcytosine Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA585516-Each-of-1 | In Stock | ₹ 46,502.50 |
PIPA585516 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,502.50
GST (18%): ₹ 8,370.45
Total Price: ₹ 54,872.95
Antigen
5-Methylcytosine
Classification
Polyclonal
Conjugate
Unconjugated
Gene Alias
5mc, 5-mC, 5-meC, 5-Methyl-cytosine, C5H7NO3
Immunogen
The immunogen used to generate this antibody corresponds to 5-MethylCytosine/ 5-mC
Quantity
100 μL
Primary or Secondary
Primary
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Target Molecule
Chemical
Applications
Dot Blot, Immunomicroscopy, Methylated DNA Immunoprecipitation
Concentration
7.55 mg/mL
Formulation
PBS with 20% glycerol and 0.025% ProClin 300, pH 7
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Target Species
Chemical
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Keep as concentrated solution
- Store product as a concentrated solution
- Centrifuge briefly prior to opening the vial
- Methylation of DNA cytosine bases plays important roles in the regulation of gene transcription
- It has been estimated that 60 to 90% of the cytosines in CpG dinucleotides are methylated
- An increase in methyl-CpG correlates with transcriptional silencing for the whole chromosome especially in developmentally regulated genes
- Methylation is believed to lead to transcriptional silencing by multiple mechanisms including alteration of transcription factor binding to promoters and alteration in chromatin structure.