PIPA587109

ADAM10 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA587109-Each-of-1 In Stock ₹ 52,332.00

PIPA587109 - Each of 1

₹ 52,332.00

In Stock

Quantity

1

Base Price: ₹ 52,332.00

GST (18%): ₹ 9,419.76

Total Price: ₹ 61,751.76

Antigen

ADAM10

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Adam10

Gene Alias

1700031C13Rik, a disintegrin and metallopeptidase domain 10, a disintegrin and metalloprotease domain (ADAM) 10, a disintegrin and metalloprotease domain 10, a disintegrin and metalloproteinase, AD10, AD18, ADAM, ADAM 10, ADAM metallopeptidase domain 10, ADAM10, ADAMs, CD156c, CDw156, Disintegrin and metalloproteinase domain-containing protein 10, HsT18717, KUZ, kuzbanian, kuzbanian protein homolog, MADM, Mammalian disintegrin-metalloprotease, metalloendopeptidases, metalloproteinase, myelin-associated metalloproteinase, RAK

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

102, 11487, 29650

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunocytochemistry, Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide, pH 7.2

Gene Accession No.

O14672, O35598, Q10743

Gene Symbols

Adam10

Immunogen

Recombinant protein of human ADAM10

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Proinflammatory cytokine tumor necrosis factor-a (TNF-a) contributes to a variety of inflammatory responses and programmed cell death
  • Notch receptor and its ligand participate in cell fate decisions during vertebrate development and are associated with several human disorders, including a T-cell lymphoma
  • TNF-a, notch and its ligand delta are all membrane-bond molecules, which are cleaved by proteases to release mature proteins or functional receptor
  • ADAM10, a metalloprotease-disintegrin in the family of mammalian ADAM (for a disintegrin and metalloprotease), was recently identified to cleave TNF-a, notch and its ligand delta (1-3)
  • The genes encoding human, mouse, and bovine ADAM10 were recently cloned and designated ADAM 10, kuzbanian (KUZ), and MADM, respectively
  • ADAM10 mRNA is expressed in a variety of human and bovine tissues.