PGA5 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA588884-Each-of-1 | In Stock | ₹ 46,057.50 |
PIPA588884 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,057.50
GST (18%): ₹ 8,290.35
Total Price: ₹ 54,347.85
Antigen
PGA5
Classification
Polyclonal
Conjugate
Unconjugated
Gene
Pga5
Gene Alias
1110035E17Rik, Pepf, pepsin A, pepsin A-5, Pepsin F, Pepsinogen 5, pepsinogen 5, group I, pepsinogen 5, group I (pepsinogen A), pepsinogen A, pepsinogen A precursor, pepsinogen A5, pepsinogen F, pepsinogen F protein, pepsinogen precursor, pepsinogen-5, Pg5, PGA, PGA3, PGA4, PGA5
Host Species
Rabbit
Purification Method
Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
5222, 58803, 60372
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Western Blot
Concentration
0.66 mg/mL
Formulation
PBS with 50% glycerol and 0.01% thimerosal, pH 7.3
Gene Accession No.
P0DJD9, Q9D106
Gene Symbols
Pga5
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 63-180 of human PGA5 (NP_0550391)
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Immunogen sequence: VDEQPLENYL DMEYFGTIGI GTPAQDFTVV FDTGSSNLWV PSVYCSSLAC TNHNRFNPED SSTYQSTSET VSITYGTGSM TGILGYDTVQ VGGISDTNQI FGLSETEPGS FLYYAPFD; Positive Samples: U-87MG, HT-29, 293T, Mouse brain, Mouse stomach, Rat brain PGA5: Pepsinogen 5, group I (pepsinogen A)
- Pepsinogens are the inactive precursors of pepsin, the major acid protease found in the stomach
- Pepsin is one of the main proteolytic enzymes secreted by the gastric mucosa
- Pepsin consists of a single polypeptide chain and arises from its precursor, pepsinogen, by removal of a 41 amino acid segment from the N-terminus
- Pepsinogen is synthesized in the stomach lining, and hydrochloric acid, also produced by the gastric mucosa, is necessary to convert the inactive enzyme and to maintain the optimum acidity (pH 1-3) for pepsin function
- Pepsin is particularly effective in cleaving peptide bonds involving aromatic amino acids
- Pepsin shows extremely broad specificity; although bonds involving phenylalanine and leucine are preferred, many others are also cleaved to some extent
- PGA5 is a member of the subfamily A1 within the pepsin family and is the predominant endopeptidase in the gastric juice of vertebrates
- PGA5 is inhibited by ovUS-1, a uterine serpin.